from tkinter import *

def click1():

   lbl.configure(text="Вы нажали кнопку 1", font=("",20),bg="cyan2")

   window["bg"] = "cyan2"

def click2():

   lbl.configure(text="Вы нажали кнопку 2", font=("",20),bg="yellow")

   window["bg"] = "yellow"

window = Tk()

window.resizable(False,False)

window.title("ПР_14: ФИО")

window.geometry('600x400')

lbl = Label(window, text="", font=("", 50))

btn = Button(window, text="Кнопка 1", command=click1)

btn.grid(column=1, row=0)

lbl.grid(column="5",row="0")

btn = Button(window, text="Кнопка 2", command=click2)

btn.grid(column=3, row=5)

window.mainloop()